Help Shape the Future of atrial fibrillation Treatment
Atrial Fibrillation
Join our heart research at 4MCS and help us find better treatments for millions of people with this heart condition across the UK.
Are You Eligible?
Who May Be Eligible to Take Part?
You may be eligible for our atrial fibrillation clinical trials if you:
Additional eligibility criteria may apply. Our research team will discuss full eligibility requirements with you during your initial consultation.
Are aged 65-74 years
Diagnosed with atrial fibrillation or atrial flutter
Are not currently taking blood-thinning medication
Live within distance of our Ilford or Swinton facility
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Current Trials
Atrial fibrillation (AF) affects over 1.5 million people in the UK. Many people with this heart condition can't get the best treatments. If you join our research study, you could help us create better treatments and help people feel better every day.
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What is Atrial Fibrillation?
Atrial fibrillation happens when your heart doesn’t beat regularly. Your heart should beat in a steady rhythm, but with AF, it beats too fast or skips beats. This makes it much more likely that you could have a stroke. Read our detailed guide on understanding atrial fibrillation, its symptoms, and why early detection matters.
What you might notice:
- Your heart feels like it's racing or jumping around
- Feeling out of breath when you move around
- Chest feels uncomfortable
- Feeling dizzy or very tired
Many people with AF don’t feel anything different at all. This makes it hard to know you have it. But even if you feel fine, AF still makes you more likely to have a stroke. If you’re experiencing heart symptoms that concern you, our clinical trials may be able to help.
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How does it work?
Register Your Interest
Complete our secure online form or call us on 03300 575 838 to express your interest. We’ll ask you some basic questions about your AF diagnosis, current medications, and medical history. This initial conversation is completely confidential and helps us understand if our current trials might be suitable for you. Read our guide on how to take part in clinical research in the UK.
Attend Your Screening Visit
If you appear eligible, we’ll invite you to our Ilford or Swinton facility for a comprehensive cardiovascular assessment. During this visit, our experienced research team will review your medical history, assess your heart rhythm, and evaluate your individual risk factors. Find out what happens at a clinical trial screening visit to help you prepare. We’ll answer all your questions and ensure you fully understand what participation involves before you make any decisions.
Begin Your Trial Participation
Once confirmed as eligible and you’ve provided your informed consent, you’ll begin the trial. You’ll attend regular visits to our facility where you’ll receive expert cardiovascular monitoring, heart rhythm assessments, and comprehensive health checks. Our dedicated team will support you throughout the entire process, ensuring your safety, comfort, and wellbeing at every stage.
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Why AF Clinical Research Matters
Atrial fibrillation trials are essential for developing better treatments, especially for persistent AF and drug-refractory cases where standard treatments may not work effectively. Discover why clinical trials are so important for advancing heart health treatments.
Current treatment challenges:
- Antiarrhythmic drugs don't work for everyone
- Rate control strategies may not prevent long-term complications
- Some patients cannot tolerate blood-thinning medications
- Ablation procedures and ablation systems need continuous improvement
What we’re trying to achieve:
- Test new ways to treat persistent AF
- Help people feel better day-to-day (improve quality of life)
- Find safer ways to prevent strokes
- Discover better options when normal medicines don't work (drug-refractory cases)
Over 1.5 million people have been told they have AF
AF makes you 5 times more likely to have a stroke
1 in 5 strokes happen because of AF
About 270,000 people have AF but don't know it yet
Participating atrial fibrillation clinical research
How You Can Benefit from Participating
Taking part in our atrial fibrillation clinical research trials offers several potential benefits. Read about the real value of joining a clinical trial.
Expert Care
- Heart specialists will check on you regularly
- We'll monitor your heart rhythm carefully
- We'll look at what might put you at risk (your risk factors)
- You'll get professional help throughout the clinical trial
Helping Others
- Help create better treatments for future patients
- Support research into safer heart rhythm medicines (anti-arrhythmic drugs)
- Help us understand how to manage AF better over time (long term)
- Help improve heart procedures (ablation system technologies)
Possible Benefits for You
- We'll keep a close eye on your condition
- You might get access to new treatments
- You'll learn more about your personal chances of having a stroke (risk of stroke)
- Better health management over time (long term)
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Why Choose 4MCS?
You may be eligible for our atrial fibrillation clinical trials if you:
Established Expertise:
Specialist clinical research facility with extensive cardiovascular trial experience since 2018. Learn more about us.
Proven Track Record:
Successfully conducted trials across all phases, contributing to medical advancements in heart rhythm treatments and stroke prevention. Read what our participants say.
Patient-Centred Care:
Comprehensive support for over 35,000 patients across various conditions, ensuring personalised care throughout your trial participation. Read what you should know before participating in a clinical trial.
Comprehensive Support:
Dedicated team provides ongoing support from initial enquiry through trial completion. View our FAQs for answers to common questions.
Enquire to participate
Become A Participant
clinical trials
Frequently Asked Questions
We understand you may have questions about participating in our atrial fibrillation clinical trial. Here are answers to some of the most common questions we receive from potential participants. For more information, visit our full FAQs page or browse our Information Hub.
You need to be 65-74 years old with confirmed atrial fibrillation or atrial flutter, and not currently taking blood-thinning medication. Our team will assess your medical history, current treatments, and overall health during your initial consultation. If you’re unsure whether your heart symptoms indicate atrial fibrillation, we can help you understand more.
We’ll review your specific type of AF (whether persistent, long-standing persistent, or other forms) and evaluate your individual risk factors. Read our guide on what is atrial fibrillation and why it matters to learn more about the condition. Even if you’re unsure about eligibility, contact us for a no-obligation assessment.