Have you noticed your heart racing, fluttering or skipping beats? These could be signs of atrial fibrillation (AF), one of the most common heart rhythm problems in the UK. If you have been experiencing unusual heart symptoms, you are not alone. Over 1.5 million people in the UK live with this condition.
At 4MCS, we are running atrial fibrillation clinical trials to help find better treatments for people with this heart condition. This blog explains what symptoms to look out for and how you could take part in research that might help millions of people.
What is Atrial Fibrillation?
Atrial fibrillation happens when your heart does not beat in its normal, steady rhythm. Instead of beating regularly, the upper chambers of your heart (called the atria) quiver or flutter. This means your heart cannot pump blood as well as it should.
AF is the most common type of irregular heartbeat. It becomes more likely as you get older, with around 1 in 10 people over 80 affected.
Common Symptoms of Atrial Fibrillation
Many people with AF notice something is not quite right with their heart. However, some people have no symptoms at all and only find out they have AF during a routine health check.
| Symptom | What It Feels Like |
|---|---|
| Palpitations | Your heart feels like it is racing, pounding, fluttering or missing beats |
| Fatigue | Feeling unusually tired, even when you have not been active |
| Shortness of breath | Getting out of breath more easily than usual, especially during everyday activities |
| Dizziness | Feeling lightheaded or faint |
| Chest discomfort | A strange or uncomfortable feeling in your chest |
If you notice any of these symptoms, it is important to speak with your GP. They can check your pulse and arrange further tests if needed.
Why Does AF Matter?
Atrial fibrillation is not life-threatening on its own, but it does need to be taken seriously. When your heart beats irregularly, blood can pool and form clots. If a clot travels to your brain, it can cause a stroke.
People with AF are five times more likely to have a stroke than those without the condition. The good news is that with the right treatment and care, most people with AF can live full, active lives.
For more detailed information about atrial fibrillation symptoms, causes and treatments, the British Heart Foundation provides an excellent guide.
How Are Heart Clinical Trials Helping?
Clinical trials are essential for finding better treatments for heart conditions like AF. Current treatments work well for many people, but not everyone responds the same way. Some people cannot take certain medications, while others find that standard treatments do not control their symptoms.
This is where research comes in. Heart clinical trials test new approaches to treating AF, including new medications and better ways to prevent strokes.
About 4MCS Atrial Fibrillation Clinical Trials
4MCS is a specialist clinical research company with facilities in Ilford (London) and Swinton (Manchester). Established in 2019, we have over 130 years of combined team experience in clinical trials and the pharmaceutical industry. Our research facilities are MHRA-approved, meaning all our trials meet strict UK safety and quality standards.
We are currently running atrial fibrillation clinical trials to test new treatments. By taking part, you could help researchers understand how to better manage AF and reduce the risk of complications like stroke.
Who Can Take Part?
You may be eligible for our AF trial if you:
- Are aged 65 to 74 years old
- Have been diagnosed with atrial fibrillation or atrial flutter
- Are not currently taking blood-thinning medication
- Can travel to our Ilford or Swinton (Manchester) facility for appointments
Our research team will discuss the full eligibility requirements with you during your initial consultation.
What Happens During a Trial?
Taking part in our atrial fibrillation clinical trials involves three simple steps:
Step 1: Register your interest. Complete our online form or call us on 03300 575 838. We will ask some basic questions about your health and AF diagnosis.
Step 2: Attend a screening visit. If you appear eligible, we will invite you to our Ilford or Swinton facility for a full health assessment. Our team will explain everything and answer your questions before you decide whether to take part.
Step 3: Begin participation. Once you give your consent, you will start the trial. This involves regular visits for heart monitoring and health checks.
Benefits of Taking Part in Heart Research
Participants in our atrial fibrillation clinical trials receive:
- Regular monitoring by heart specialists
- Thorough health assessments throughout the trial
- Access to potential new treatments before they become widely available
- The chance to contribute to research that could help millions of people with AF
All trial procedures follow Good Clinical Practice guidelines and are overseen by the MHRA to protect your safety and wellbeing.
Why Choose 4MCS?
4MCS has a strong track record in clinical research. Our team has successfully conducted trials across Phase 1b to Phase 4, contributing to medical advances in heart rhythm treatments and stroke prevention.
We maintain a database of over 35,000 patients and are committed to providing personalised care throughout your participation. Our friendly, professionally trained staff create a comfortable and supportive environment for all participants.
Ready to Find Out More?
If you have atrial fibrillation and are interested in taking part in heart research, we would love to hear from you.
Call us on 03300 575 838 or email volunteer@4mcs.co.uk to speak with our research team. There is no obligation at this stage. We are simply here to answer your questions and help you decide whether a clinical trial might be right for you.
Taking part in research is a personal decision, but it is also a chance to play an active role in your own healthcare while helping to shape the future of AF treatment for others.
4MCS is a privately owned clinical research company specialising in Phase 1b to Phase 4 trials. Our Ilford and Swinton facilities are MHRA-approved and operate in partnership with the NHS.
