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Fatty Liver Disease

Metabolic-associated steatotic liver disease (MASLD), commonly known as fatty liver disease, is a condition where too much fat builds up in the liver. Over time, this can cause the liver to become inflamed and scarred, which can affect how well it works.

MASLD is often linked to other health conditions and may not cause any obvious symptoms in its early stages. This means many people do not realise they have it until it is picked up during tests for something else.

This study is available at our Manchester and London clinics. Participants may receive up to £2,548 for their time and commitment.

Fatty liver disease is more common in people with certain health conditions, including:

  • Type 2 diabetes
  • Obesity (a body mass index of 30 or higher)
  • High blood pressure (hypertension)
  • High cholesterol or abnormal blood fat levels (dyslipidaemia)

Having one or more of these conditions may increase your risk of developing fatty liver disease.

  • Are 18 years of age or older
  • Have been diagnosed with fatty liver disease, including: Non-alcoholic fatty liver disease (NAFLD), Non-alcoholic steatohepatitis (NASH), Fatty liver. Have at least one related health condition, such as type 2 diabetes, obesity, high blood pressure or high cholesterol.
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clinical trials

Frequently Asked Questions

We understand you may have questions about participating in our clinical trial. Here are answers to some of the most common questions we receive from potential participants. For more information, visit our full FAQs page or browse our Information Hub.

What is a fatty liver disease clinical trial?
A fatty liver disease clinical trial is a medical research study that tests new treatments for conditions like NAFLD (non-alcoholic fatty liver disease) and MASH (metabolic dysfunction-associated steatohepatitis). These studies help researchers find out whether new medicines are safe and work well. Volunteers who take part receive close monitoring from healthcare professionals and may get access to treatments not yet available to the public.
You may be eligible if you are aged 18 to 75 and have been diagnosed with fatty liver disease or MASH. You might also qualify if you have risk factors such as type 2 diabetes, high blood pressure, high cholesterol, or a BMI between 25 and 50. Each study has its own requirements, so you would need to complete a screening process to check if you are suitable.
During the trial, you will attend regular appointments where the research team will monitor your health. This typically includes blood tests, physical examinations, and liver scans such as a FibroScan to check for fat build-up and stiffness. Some trials may also require a liver biopsy. You will receive either the study treatment or a placebo, and the team will track how your body responds over several weeks or months.
Most clinical trials offer compensation for your time and travel expenses. The amount varies depending on the study length and the number of visits required. All study-related assessments, scans, and treatments are provided free of charge. You can leave the trial at any time without giving a reason, and this will not affect your regular medical care.

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03300 575 838

volunteer@4mcs.co.uk

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